| From Kansas City, MO | 88 miles | Take I-70 East to Highway 65 South to Sedalia, or take Highway 50 East from K.C. to Sedalia |
| From St. Louis, MO | 191 miles | Take I-70 West to Highway 65 South to Sedalia, or take Highway 50 West from St. Louis to Sedalia |
| From Columbia, MO | 67 miles | Take I-70 West to Highway 65 South to Sedalia, or take Highway 50 West from St. Louis to Sedalia |
| From Springfield, MO | 118 miles | Take Highway 65 North to Sedalia |
| From Jefferson City, MO | 61 miles | Take Highway 50 West to Sedalia |
| From Marshall, MO | 30 miles | Take Highway 65 South to Sedalia |
| Sedalia Memorial Airport | 1900 East Boonville 660-826-4128 |
| Kansas City International Airport | 601 Brasilia Ave Kansas City, MO 816-243-5237 |
| American Auto Rental* | 2101 South Limit 660-827-5200 |
| Enterprise Rent-A-Car | 2409 W. Broadway 660-827-3575 |
* = Member of the Sedalia Area Chamber of Commerce
| Amtrak | Schedules Available at the Katy Depot at 600 E. 3rd 100 block of Main St 1-800-USA-Rail |
| A+ Victory Shuttle & Taxi | KCI Airport, Katy Trail, Medical runs, In town Taxi Service, call for other destinations. 660-221-7783 660-221-7795 |
| B - L Airport Shuttle* | Specializing in Airport Shuttle Service 660-221-4406 |
| Lee's Taxi Services | 660-827-2701 |
* = Member of the Sedalia Area Chamber of Commerce
| OATS | Click here to view schedule. 660-827-2611 |
| The Bus | Click here to view schedule. 660-826-4212 |